منابع مشابه
Experimental Brain Tumors: Current Concepts
The possibility of having experimental models of brain tumors allows for testing therapies applicable to human brain tumors. They can be induced by viruses, chemicals or radiation. Radiation-induced brain tumors have seldom been used, but diverse virus groups have been used to induce brain tumors. Among DNA viruses, both adenoviruses and papovaviruses have been shown to induce brain tumors in a...
متن کاملExperimental Brain Tumors I. Tumors Produced with Methylcholanthrene*
Efforts to produce intracranial neoplasia by various chemical carcinogens have been attended with scant success prior to the work of Seligman and Shear (2). By intracerebral implantation of pellets of 2o-methylcholanthrene, these workers produced i i gliomas and 2 fibrosarcomas in a series of 2o male mice of the C3H strain. Seligman and Shear reported also successful subcutaneous transplantatio...
متن کاملChemotherapy of experimental metastatic brain tumors in female Wistar rats.
. â€M̃etastatic' †̃ brain tumors were produced in female Wistan rats by intracarotid inoculation of Walker 256 carcinoma cells and subsequent treatment with small doses of cycbophospha mide (CTX) which eradicated extnacnanial tumors, giving time for intracranial tumors to grow. Seven drugs currently in use for brain tumor chemotherapy were tested using this model. After toxicity for each drug w...
متن کاملExperimental nodel of C6 brain tumors in athymic rats.
Malignant brain tumor experimental models tend to employ cells that are immunologically compatible with the receptor animal. In this study, we have proposed an experimental model of encephalic tumor development by injecting C6 cells into athymic Rowett rats, aiming at reaching a model which more closely resembles to the human glioma tumor. In our model, we observed micro-infiltration of tumor c...
متن کاملChemotherapy of Experimental Metastatic Brain Tumors in Female Wistar Rats1
. â€M̃etastatic' †̃ brain tumors were produced in female Wistan rats by intracarotid inoculation of Walker 256 carcinoma cells and subsequent treatment with small doses of cycbophospha mide (CTX) which eradicated extnacnanial tumors, giving time for intracranial tumors to grow. Seven drugs currently in use for brain tumor chemotherapy were tested using this model. After toxicity for each drug w...
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ژورنال
عنوان ژورنال: Neurologia medico-chirurgica
سال: 1961
ISSN: 0470-8105,1349-8029
DOI: 10.2176/nmc.3.187a